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Sep 2026

Paleogenomics and habitat modeling reveal temperate Eurasian origins of woolly rhinoceroses.

The woolly rhinoceros was a prominent Ice Age megafaunal species, and there is limited knowledge regarding its origin and responses to past glacial cycles. We sequenced 29 mitochondrial and 14 nuclear genomes from Pleistocene specimens across Eurasia and modeled the species' habitats over the past 500,000 years. Our re...

X. Lei, J. Ruan, Xue Liang et al. · 0 citations
Open access Aug 2026

A multiplex genome editing pipeline for rapid combinatorial trait engineering.

Current de-extinction efforts center on editing the genomes of extant species to express key traits that evolved in closely related extinct species. These complex projects require advances in genetic engineering pipelines coupled with animal model production as an approach to test hypotheses about genotype and phenotyp...

Rui Chen, M. Coquelin, Kanokwan Srirattana et al. · 0 citations

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