OBJECTIVES
Hypertransaminasemia is a frequent finding in hospitalized children with common pediatric illnesses, often considered a transitory phenomenon associated with systemic inflammation/injury. This study aims to assess the prevalence and causes of incidentally detected hypertransaminasemia in children admitted to...
A. Di Giorgio, G. Ranucci, Pietro Aliberti et al.· Journal of Pediatric Gastroe...· 0 citations
Hepatotoxicity remains one of the most frequent and clinically important safety concerns in adeno-associated virus (AAV) gene therapy. Yet the laboratory patterns observed after vector administration are biologically complex and often difficult to interpret. Alanine aminotransferase (ALT) and aspartate aminotransferase...
B. Henry, B. Bénichou, M. Y. Rincon et al.· Clinical Biochemistry· 0 citations
Current evidence supports improvements in pruritus and serum bile acid control, particularly in PFIC2/BSEP deficiency; however, treatment responses are heterogeneous and additional long-term clinical and economic evidence is needed.
S. Horslen, G. Vogel, Jolan Terner-Rosenthal et al.· Journal of Comparative Effec...· 1 citation
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