L. De Graeve

Detaching Photosensitive Nanoparticles from Cells Prevents Them from Remaining in Cells after Photoporation

ABSTRACT Efficient and safe intracellular delivery of macromolecules, like nucleic acids, remains a major challenge in ex vivo cell engineering. While photoporation is a highly attractive method for cytosolic delivery of (macro)molecules, photosensitizers remaining in the photoporated cells may pose safety concerns, es...