Author

L. de Haan

3 papers indexed here

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Open access Sep 2026

Longitudinal White Matter Microstructure and Transition to Psychosis in Individuals at Clinical High Risk

Altered white matter microstructure, commonly indexed by fractional anisotropy (FA), has been reported in individuals at clinical high-risk of psychosis (CHR-P) across multiple white matter tracts. However, the relationship between these alterations and later transition to psychosis remains unclear. To address this gap...

Lara Bolte, George Gifford, M. Serpa et al. · bioRxiv · 0 citations

Open access Sep 2026

The role of self-disturbance phenomena and negative-self schemas in the relationship between childhood trauma and psychotic experiences in patients with psychosis, unaffected siblings and healthy controls

Abstract Background Childhood trauma increases the risk for psychosis. However, mechanisms underlying this relationship remain unclear. In the present study, we aimed to investigate whether negative cognitive self-schemas or basic self-disturbance mediate the association between childhood trauma subtypes (abuse and neg...

A. Jelsma, Justine de With, M. van der Pluijm et al. · Psychological Medicine · 0 citations

Open access Jul 2026

C-reactive protein polygenic risk is associated with obesity-related traits in schizophrenia spectrum disorders

Background Patients with schizophrenia spectrum disorders (SSDs) are at increased risk of cardiometabolic dysregulations, which substantially contribute to cardiovascular morbidity and reduced life expectancy. Chronic low-grade inflammation is a key factor in the development of cardiometabolic outcomes. Polygenic risk...

Chenxu Zhao, E. Naderi, T. Habtewold et al. · Frontiers in Psychiatry · 0 citations