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Open access Aug 2026

H2-O deficiency in B cells or dendritic cells drives retrovirus-neutralizing antibody responses

ABSTRACT Major histocompatibility complex class II (MHC II)-restricted antigen presentation is central to CD4+ T-cell activation and the generation of high-affinity, class-switched antibody (Ab) responses. Peptide loading of MHC II in endosomal compartments is modulated by the functional interplay of two nonclassical M...

Julie A. Dobkin, Ryan Fink, Helen Beilinson Lietuvninkas et al. · 0 citations

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