Author

L. Dyrskjøt

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Meta-analysis Open access Aug 2026

Multi-population GWAS meta-analysis identifies bladder cancer susceptibility loci and highlights genetic regulation of smoking-related risk

A multi-population meta-analysis of genome-wide association studies, including 32,470 individuals with and 1,753,462 without bladder cancer, identifies 70 independent risk loci, of which 43 are novel, and uses experimental approaches to uncover how inherited variation influences this risk in the context of smoking.

L. Prokunina-Olsson, O. Flórez-Vargas, Michael G. Levin et al. · Nature Communications · 0 citations

Open access Aug 2026

FGFR3-driven gene regulatory network analysis reveals a protumoral role for p63 in luminal bladder tumors

Findings support p63 as a protumorigenic regulator in FGFR3-mutated tumors despite their luminal differentiation and provide a detailed FGFR3-driven GRN, offering insights into FGFR3-induced oncogenic dependency and potential strategies to circumvent resistance to FGFR inhibitors.

A. Moreno-Vega, M. Zambrano, Lilia Estrada-Virrueta et al. · Journal of Clinical Investig... · 0 citations