Author

L. Elo

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Open access Sep 2026

A candidate CD4⁺ T-cell gene expression panel for multiple sclerosis highlights MgADP-associated genes.

Multiple sclerosis (MS) is an autoimmune disease characterized by immune cell dysregulation. HLA class II alleles drive the disease risk, thereby highlighting CD4+ T cells as central contributors to MS initiation. While genome-wide association studies have identified additional non-HLA genetic risk loci, the mechanisms...

Hai-Feng Xu, M. Venäläinen, Tone Berge et al. · Multiple Sclerosis and Relat... · 0 citations

Open access Aug 2026

Prediction of platinum-based neoadjuvant chemotherapy response in muscle-invasive bladder cancer using a multifaceted approach

Radical cystectomy (RC), preceded by platinum-based neoadjuvant chemotherapy (NAC), is recommended for eligible patients with muscle-invasive bladder cancer (MIBC). Although NAC improves survival, many patients do not respond; in non-responders, it may delay surgery and cause toxicity. Predictive biomarkers to guid...

Arian Askari, Mehrad Mahmoudian, T. Lamminen et al. · Scientific Reports · 0 citations

Open access Aug 2026

Individualized transcriptomic changes in malignant and benign prostate identify markers of disease recurrence

Better tools to predict the likelihood of a recurrence of prostate cancer (PC) after a radical prostatectomy are needed and would provide more personalized therapies for the patients early enough to efficiently control the disease burden. In this study, the transcriptome profiles from matched malignant and adjacent...

Julia Mathlin, K. Rytkönen, A. Laiho et al. · Scientific Reports · 0 citations