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Open access Aug 2026

Sustained benefit of adjuvant olaparib in women with germline BRCA1- and BRCA2- -associated high-risk HER2-negative early breast cancer: Updated results from the OlympiA phase III trial.

BACKGROUND The randomised phase III OlympiA trial (NCT02032823) compared 1 year of adjuvant olaparib (oral poly-(ADP-ribose) polymerase [PARP] inhibitor) to placebo in 1,836 patients with pathogenic/likely pathogenic BRCA1 or BRCA2 (gBRCApv) germline variants and high-risk human epidermal growth factor receptor 2 (HER2...

J. Garber, D. Cameron, C. Campbell et al. · 1 citation
Open access Sep 2026

Sociodemographic and Clinicopathologic Characteristics of Patients With Invasive Breast Cancer in Latin America: The LATINA Breast Cohort (LACOG 0615/MO39485).

PURPOSE Breast cancer (BC) is the most common malignancy in women and a leading cause of cancer-related mortality in Latin America (LATAM). This region is characterized by marked disparities in incidence, mortality, and care delivery, yet these differences have not been systematically examined. METHODS The LATINA stu...

G. Werutsky, Cynthia Villarreal-Garza, A. Ferrigno Guajardo et al. · 0 citations

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