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Author

L. Fischer

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Open access Aug 2026

Optogenetic control of actin crosslinker length reveals a mechanical basis for cortical symmetry breaking

Cell shape changes during migration, division, or differentiation require the dynamic regulation of actin network mechanics. Actin crosslinkers are central to this regulation, controlling network connectivity and the transmission of contractile forces. A large diversity of crosslinkers exists, differing in length, doma...

Filipe Nunes Vicente, Anumita Jawahar, Michael Wassermair et al. · 0 citations
Open access Sep 2026

The membrane-to-cortex distance regulates mDia1 activity to control cortical mechanics

The shape of animal cells is controlled by their surface, which comprises the cell cortex, a peripheral actin network, tethered to the plasma membrane by membrane-to-cortex attachment proteins. Changes in cortical components have long been considered to dominate the regulation of forces and mechanical properties at the...

Léanne Strauss, Sergio Lembo, Samuel F. Gérard et al. · 0 citations

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