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Review Sep 2026

Personalized Therapy in Advanced Cholangiocarcinoma: Contemporary Treatment Approaches and Future Directions.

Cholangiocarcinoma (CCA) includes a heterogeneous group of malignancies arising from the biliary epithelium, anatomically classified into intrahepatic, perihilar, and distal disease, with subtype-specific molecular features and treatment implications. Intrahepatic CCA is further subclassified into small- and large-duct...

F. Saj, C. B. Xavier, L. Goyal et al. · 0 citations
Review Open access Sep 2026

Promises and Pitfalls of ctDNA testing in the Management of Cholangiocarcinoma.

Diagnosis and treatment of cholangiocarcinoma is often limited by the availability of tissue biopsies for genomic analysis. Liquid biopsies using blood circulating tumor DNA (ctDNA) have emerged as a valuable and non-invasive alternative to conventional testing. ctDNA analysis has advanced the treatment paradigm for ch...

Min-Gen Liu, B. Doger, A. Pant et al. · 0 citations

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