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Author

L. Grinstein

2 papers indexed here

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Open access Oct 2026

Shared molecular pathways in pediatric genetic epilepsies: Insights from a single‐center cohort of 80 patients

Abstract Objective Genetic epilepsies in childhood are highly heterogeneous, and approaches to identify shared biological mechanisms across distinct genetic etiologies remain limited. We aimed to investigate whether genes associated with pediatric genetic epilepsies in our heterogeneous cohort converge on common functi...

L. Hecher, M. Woidy, F. Plein et al. · 0 citations
Open access Sep 2026

Reduced NLRP3, AIM2 and NLRC4 inflammasome activity in cord blood of extremely preterm infants

Background Pro-inflammatory caspase-1 is a key player in innate immunity. Physiological activation of the inflammasome/caspase-1 pathway supports host defense against pathogens, whereas dysregulated activation contributes to the pathogenesis of neonatal diseases such as bronchopulmonary dysplasia. Although preterm infan...

Hannah Siedel, Kristin Hieronymus, Jan M. Niehues et al. · 0 citations

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