Five decades of pneumococcal meningitis in Spain: a single-centre, clinical and genomic, retrospective, observational study.
BACKGROUND Pneumococcal meningitis remains a major threat, with high fatality rates and long-term sequelae, despite advances in vaccination and treatment. We aimed to examine the associations between pneumococcal serotypes, Global Pneumococcal Sequence Cluster (GPSC), antimicrobial resistance, source of infection, and...