Inhibition of endogenous TGF-β normalizes extracellular matrix deposition in hiPSC-derived fibroblasts
Fibroblasts are mesenchymal cells with essential functions for connective tissue homeostasis and repair through the production and organization of the extracellular matrix (ECM). Most reconstructed skin models used in research and skin-related applications rely on fibroblasts to produce ECM. Despite their shared func...