Combining X‑ray Diffraction, Solid-State NMR, and Computational Chemistry for Structural Insights and Performance Evaluation of GIPAW/GIAO 13C Chemical-Shift Calculations for Lamivudine and Three Pharmaceutical Salts
The increasing prevalence of polymorphism and multicomponent crystal forms in active pharmaceutical ingredients demands rigorous structural characterization tools for quality control. Here, lamivudine and three pharmaceutical salts, hydrochloride, salicylate monohydrate, and hydrogen phthalate, were investigated by com...