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Author

L. Huttunen

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Open access Sep 2026

Patient-Derived hiPSC-Cardiomyocytes and Engineered Heart Tissues Reveal Distinct Functional Phenotypes in Inherited Cardiomyopathies

EHTs generated from HCM hiPSC-derived cardiomyocytes showed a progressive decline in apparent force, whereas DCM EHTs fractured over time, suggesting mutation-associated phenotypes in 3D cardiac tissue models, and highlight the utility of hiPSC-based cardiac models for investigating molecular and functional disease mec...

S. Pohjavaara, Q. Majid, L. Huttunen et al. · 0 citations

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