Author

Lídia M. Lima

3 papers indexed here

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Review Oct 2026

Recent advances of GPR40 agonists as potential anti-Alzheimer's agents.

Alzheimer's disease (AD) is a progressive and multifactorial neurodegenerative disorder involving metabolic dysfunction, neuroinflammation, mitochondrial impairment, synaptic failure, and neuronal loss. Although amyloid-beta deposition and neurofibrillary tangles composed of hyperphosphorylated tau remain central patho...

Jefferson Muniz Alves da Silva, A. Kümmerle, D. A. Rodrigues et al. · Future Medicinal Chemistry · 0 citations

Open access Sep 2026

LASSBio-753 as a new prototype of anti-tumor necrosis factor-alpha anti-inflammatory drug.

Pain and inflammation are protective responses; however, when persistent, they can cause damage and reduce the quality of life. The limitations of current therapies underscore the importance of investigating new agents that are effective and have fewer adverse effects. Therefore, the present study aimed to evaluate the...

Tino Marcos Lino da Silva, Viviane Pinheiro Alves de Almeida, A. D. de Sousa et al. · Biomedicine & pharmacotherap... · 0 citations

Aug 2026

Preclinical characterization of the efficacy and safety of histamine H3 receptor antagonist, LINS01022, as a novel analgesic for chronic neuropathic pain treatment.

This research provides the first evaluation of LINS01022's analgesic efficacy and its favourable safety profile in neuropathic pain, and suggests that a novel H3R antagonist is a promising drug candidate and a valuable pharmacological tool for further investigation.

Magdalena Maciuszek, M. Białoń, Mateusz Królewski et al. · European Journal of Pharmaco... · 0 citations