L. Long

Euchromatin forms condensed domains with short active regions on the surface

Technological advances in chromatin structure characterization have continually refined our understanding of transcriptional regulation in eukaryotic systems. Despite these developments, achieving nucleosome-resolution structural characterization remains a significant challenge. As a result, it remains unclear what str...

Euchromatin forms condensed domains with short active regions on the surface.

RNA-guided transcriptional repression by TIGR-Tas systems

These findings establish TIGR-Tas as a functionally diverse family of RNA-guided effectors, with comprehensive annotations available through TIGRSafari, which will be made publicly available upon publication, to support further exploration and engineering.

Uncovering the signaling networks of disseminated glioblastoma cells in vivo with INSIGHT

INvestigating SIGnaling network of specific cell subpopulation in Heterogeneous Tissue, a new platform technology combining fluorescence-activated cell sorting with ultra-sensitive mass spectrometry to enable phosphoproteomic characterization of rare and discrete cell subpopulations from fixed tissues, uncovered a glob...