Quantitative T1 mapping (qT1) is a magnetic resonance imaging (MRI) biomarker of brain microstructural changes; however, its application in Alzheimer disease (AD) remains limited. We compared cortico-limbic qT1 values between patients with AD and healthy controls (HCs) and examined their relationship with amyloid burde...
L. Gualco, N. Montobbio, M. Losa et al.· European Radiology Experimen...· 0 citations
The Amyloid Imaging to Prevent Alzheimer’s Disease Prognostic and Natural History Study (AMYPAD-PNHS) multimodal magnetic resonance imaging (MRI) dataset provides open-access longitudinal MRI data of 2759 cognitively normal or mild cognitive impairment individuals, encompassing (micro-)structural, physiological, and...
L. Pieperhoff, M. Tranfa, Prithvi Arunachalam et al.· Scientific Data· 0 citations
Abstract INTRODUCTION Tau positron emission tomography (PET) probes Alzheimer's disease (AD) severity via regional tau spread but is not widely available. We tested whether multiregion structural magnetic resonance imaging (MRI) could approximate individual tau burden. METHODS We studied 378 Alzheimer's Disease Neuroim...
Martina Pulze, S. Garbarino, L. Lorenzini et al.· Alzheimer's & Dementia· 0 citations
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