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L. Lou

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Open access Sep 2026

High sperm DNA fragmentation is associated with increased embryonic chromosomal abnormality: a retrospective study of 8 years involving 5637 couples undergoing ART

Does sperm DNA fragmentation impair blastocyst chromosomal integrity? A high sperm DNA fragmentation index (DFI) is associated with an increased risk of blastocyst aneuploidy, particularly when the man has poor semen quality or when the female partner is aged ≥35 years. Evidence linking sperm DFI to...

L. Lou, Peng-Cheng Xu, P. Xie et al. · 0 citations

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