Chitosan-coated vesicles in thermosensitive gel as a compelling platform for cannabidiol treatment of ocular disorders.
Topical ocular delivery of cannabidiol (CBD), a well-known phytocannabinoid with anti-inflammatory and neuroprotective properties, remains challenging because of its poor aqueous solubility, limited bioavailability, and rapid precorneal clearance. Nanocarrier-based and thermoresponsive mucoadhesive systems have emerged...