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Duration of effectiveness of tuberculosis preventive treatment across various tuberculosis burden settings: a systematic review and individual-participant meta-analysis.
BACKGROUND Millions of individuals at risk of tuberculosis are given tuberculosis preventive treatment (TPT) annually. However, questions remain regarding the duration of protection from TPT and potential variability across populations and settings with disparate tuberculosis risk. We aimed to assess the effect of TPT...
Salivary polyreactive and SARS-CoV-2-specific antibody responses following SARS-CoV-2 infection and vaccination in healthcare workers.
SARS-CoV-2 infection, but not vaccination, induces distinct changes in the salivary IgA compartment, including polyreactive antibodies, which may reflect repeated mucosal immune stimulation and is associated with greater symptom burden.