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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

L. Mahal

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Open access Sep 2026

Elucidating the Requirements for microRNA-Mediated Upregulation Enables Reengineering of Upregulatory Sites.

The post-transcriptional regulation of protein expression by miRNA has given rise to new technologies for therapeutic interventions and synthetic biology. To date, these technologies assume that miRNAs are repressors of protein expression; however, emerging evidence has shown that miRNA regulation of proteins is bidire...

H. Harati, Thusini Uggalla Arachchige, Xing-Hai Liu et al. · 0 citations
Open access Sep 2026

The Parkinson 's Disease Associated BAP1/ASXL3 Complex Regulates the Internalization of α-Synuclein Fibrils by Reprogramming the Cell Surface Glycoproteome

A central hallmark of Parkinson's disease (PD) is the spread of -Synuclein (-Syn) aggregates, which is thought to contribute to its progressive nature. To better understand the mechanism of cellular internalization of -Syn fibrils, we conducted a genome wide CRISPR activation (CRISPRa) screen to identify genetic modifi...

N. Karpilovsky, T. Goiran, K. Senkevich et al. · 0 citations

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