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Author

Laura Morelli

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Oct 2026

Abstract B091: Genome and Transcriptome-Wide Association Studies of HER2-positive breast cancer in Hispanic/Latina women in the United States and women in Latin America

Breast cancer is the most common cancer among women worldwide. Genome-Wide Association Studies (GWAS) have identified genetic variants associated with overall and estrogen receptor-specific breast cancer risk. However, genetic drivers of human epidermal growth factor receptor 2-positive (HER2+) disease remain poo...

J. S. Mendez, Xiao-Song Huang, P. Lott et al. · 0 citations
Open access Jul 2026

Impaired astrocyte-to-neuron cholesterol trafficking drives synaptic dysfunction in Rett syndrome

Rett syndrome (RTT) is a severe X-linked neurodevelopmental disorder caused by loss-of-function mutations in the MECP2 gene and characterized by profound impairments in neuronal maturation and synaptic connectivity. Increasing evidence indicates that astrocyte dysfunction contributes to RTT pathogenesis through non-cel...

Francesca M. Postogna, Noemi Giancroce, C. Cabasino et al. · 0 citations

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