How can theory and mathematical modeling help accelerate research in psychiatry? Here we highlight the promise of computational approaches via three recent trends: multi-scale models of working memory which link receptors and cell-types to brain-wide activity and behavior; the extension of mechanistic computational mod...
S. Froudist-Walsh, Tsvetoslav G. Ivanov, Teo Fantacci et al.· Biological Psychiatry· 0 citations
We study how network connectivity and heterogeneous phase-delays shape the spatiotemporal dynamics of finite oscillator networks. Phase-delays can destabilize global synchronization and promote phase-locked patterns, including states with uniform phase gradients and more complex combinations of these modes. Yet, how co...
K. L. Rossi, Antonio Mihara, L. Muller et al.· 0 citations
Using high-field fMRI and a novel connectivity analysis, this study found abnormal network hubs across multiple systems in FDS, supporting a predictive processing model and offering preliminary biomarkers to improve FDS differentiation, pending validation in larger cohorts.
Evidence suggesting that L3PN morphology and physiology differ significantly across PFC, PPC and V1 in primates is reviewed, suggesting a primate-enhanced regional variability that may be the substrate for area-specific L3PN vulnerability in schizophrenia.
G. González-Burgos, R. Benavides-Piccione, A. Neef et al.· Biological Psychiatry· 0 citations
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