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L. Pertea

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Review Open access Aug 2026

Molecular mechanisms of antibiotic resistance in Gram-positive and Gram-negative bacteria - a narrative review

Lariocidin, a structurally novel ribosome-targeting lasso peptide with broad-spectrum activity against both Gram-positive and Gram-negative multidrug-resistant pathogens, is presented as an emerging therapeutic scaffold that circumvents resistance mechanisms operating across both bacterial groups.

Denisa Claudia Tonco, C. Gavrilovici, Ancuța Lupu et al. · 1 citation

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