Open access
Oct 2026
Transcriptomic and epigenomic profiles analysis during human acclimatization to simulated high-altitude hypoxia
These findings identify distinct but overlapping phases of early HH acclimatization, progressing from stress and innate immune activation to lymphocyte-specific and redox remodeling and indicating that molecular adaptation extends beyond detectable systemic inflammatory activation.
A. Giannella, S. Mrakic-Sposta, A. Vezzoli et al.
· Scientific Reports · 0 citations