Open access
Jul 2026
Machine learning-assisted development of a fast Mechanochemical Johnson–Corey–Chaykovsky reaction
A machine learning-guided mechanochemical protocol enabling rapid, solvent-free cyclopropanation and epoxidation under mild, air-equilibrated conditions is reported, establishing a foundation for the integration of Machine Learning and mechanochemistry in designing industrially relevant transformations that prioritize safety and sustainability.
Francesco Mele, A. M. Constantin, Marco Barezzi et al.
· Nature Communications · 0 citations