Author

L. Schmalbrock

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Open access Aug 2026

Recurrent non-canonical proteoforms in acute myeloid leukemia identified by integrative proteogenomics

A recurrent AML dark proteome is defined and a framework for the discovery of tumor-specific non-canonical proteins for mechanistic and therapeutic studies is established.

L. Schmalbrock, Asher Preska Steinberg, Katarzyna Kulej et al. · bioRxiv · 0 citations

Jul 2026

Information-seeking failures of large language models in agentic clinical reasoning

Large language models achieve high scores on medical knowledge assessments, yet clinical reasoning requires actively deciding what to investigate under uncertainty. We developed an agentic evaluation framework in hematologic oncology in which models must proactively request clinical data across three sequential rounds...

K. Braitsch, L. Schmalbrock, Theresa Weltermann et al. · arXiv.org · 1 citation