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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

L. Schmidt

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Open access Sep 2026

Pulsed-SILAC in single mouse embryos reveals early embryonic protein synthesis dynamics and phosphosite regulation

Early embryogenesis relies extensively on maternally deposited products until zygotic genome activation, yet the dynamics for the synthesis of new proteins in mammalian embryos remains poorly characterized. To address this, we applied pulsed stable isotope labelling by amino acids in cell culture (pSILAC) combined with...

L. Schmidt, Maico Y. Lechner, Javier Martín-González et al. · 0 citations
Open access Sep 2026

Spatial proteomics identifies FXYD6 as a dual-site protein of neuromuscular junction in the diaphragm

Morphological studies of the diaphragm have provided a detailed view of its architecture, which consists of parallel skeletal muscle fibers and a central ring of neuronal innervation that includes neuromuscular junction (NMJ) units. NMJs are disease-vulnerable synapses; thus, analysis of the NMJ is essential to underst...

Nitin Eapen, L. Schmidt, M. Saynisch et al. · 0 citations

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