Parsing the Functional Heterogeneity of the Psychosis Spectrum: A Clinically Informed Application of Genomic Structural Equation Modeling
Schizophrenia, bipolar disorder, and major depression vary in their age of onset, cognitive impacts, degree of impairment, and clinical course. However, since psychosis is a transdiagnostic feature that occurs across all three of these disorders, they can be represented as a spectrum. We leveraged genomic data to explo...