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Author

Lorenz Studer

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Open access Sep 2026

Decoding subtype development and function in human pluripotent stem cell-derived midbrain dopaminergic neurons

Midbrain dopaminergic (mDA) neurons comprise molecularly and functionally distinct subtypes with differential vulnerability in neurodegenerative and psychiatric disorders. However, the mechanisms specifying subtype identity remain poorly understood, and protocols for the selective derivation of human mDA subtypes are l...

Dong-He Yang, Sejoon Choi, Jing-Hua Piao et al. · 0 citations
Review Aug 2026

Induced pluripotent stem cells from discovery to translation

This Review evaluates the technological and translational trajectories that have defined the iPSC era and analyzes the operational barriers to therapeutic development, envisioning a paradigm shift in which iPSC-derived interventions transition from bespoke experimental models toward standardized, engineered biological...

Jaecheol Lee, Todd J. Herron, L. Studer et al. · 0 citations

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