Animal viruses depend on host membranes at every stage of infection, yet membrane lipid states are often treated as background rather than as causal determinants of virus-host interactions. This Review develops a phospholipid-code framework in which headgroup identity, acyl-chain chemistry, leaflet topology, and lipid...
L. Tan, Guo-Yuan Wen· Frontiers in Cellular and In...· 0 citations
Protection was accompanied by an increased frequency of splenic CD3 + CD8 + T cells, particularly after booster immunization, suggesting a role for cellular immunity alongside neutralizing antibodies.
Fei Wang, Jia-Nan Xie, Guo-Yuan Wen et al.· Frontiers in Immunology· 0 citations
This study is the first to identify circRNA0857 as a critical regulator in NDV infection, elucidating its role in enhancing NDV-induced autophagy via the miR1709/ATG3 and miR1746/ATG7 signaling axes.
Siyuan Wang, Yang Qu, Weiwei Liu et al.· Journal of Virology· 0 citations
The PLpro-TM protein is identified as a pan-coronavirus antagonist of nucleocytoplasmic trafficking and innate immune response and established PLpro-TM-mediated cleavage of Importin α1 as a conserved immune evasion strategy across coronaviruses and highlights this interaction as a potential target for broad-spectrum an...
Jie-Huang Wang, Wenxiang Xue, Ying-Jie Sun et al.· bioRxiv· 0 citations
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