L. Temmerman

Autocrine feedback maintains homeostatic neuropeptide expression in a peptidergic hub neuron.

Neuronal circuits sustain stable function by self-regulating their gene expression and neurosecretion. Patterns for autocrine feedback by neuropeptides are widespread across nervous systems, but how they contribute to neuronal homeostasis is less well understood. Here, we identify an autocrine homeostatic mechanism in...