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L. V. Schneider

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Open access Sep 2026

Innervated human cardiac muscle model reveals sympathetic drivers of KCNH2-associated arrhythmias

Cardiac autonomic neurons regulate contractility. Autonomic nervous system dysregulation can cause sympathetic overdrive, leading to heart failure, and fatal arrhythmias. Here, we introduce innervated engineered human myocardium (iEHM), a model of neuro-cardiac junctions, constructed by fusing sympathetic neuronal orga...

L. V. Schneider, Michael Gani Setya, Guobin Bao et al. · 0 citations

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