Open access
Jul 2026
Multi-level precise regulation of gene transcription in the yeast Saccharomyces cerevisiae based on light-sensitive CRISPR/Cas systems
The gene regulatory approaches at the translational and post-translational levels were integrated with optogenetic control patterns to attain very sensitive multi-level precision regulation of the dCas9 protein, thereby facilitating flexible regulation of transcription levels of target genes.
Yaokun Liang, Xianghui Qi, Song Gao et al.
· Nucleic Acids Research · 0 citations