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Author

L. Vandenberghe

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Open access Aug 2026

Functional evaluation of a natural AAV capsid liver targeting motif in human hepatocytes

The results showed the potential of a combinatorial AAV library for model validation and revealed the human microliver platform-PEG as a reliable system for the development of AAV therapeutics.

Carmen Unzu, Amanda X. Chen, Liliana Mancio-Silva et al. · 0 citations
Open access Jul 2026

In vivo gene disruption and homology-directed repair in muscles and muscle stem cells using CRISPR/Cas9

It is found that postnatal cardiac muscle, skeletal muscle, and muscle stem cells undergo templated HDR at different rates across discrete developmental stages in mice, and in neonatal mice, editing in neonatal mice yielded more efficient HDR in cardiac tissue.

Bryan L. Peacker, Kuan-Hung Lin, A. Lam et al. · 0 citations