The role of phytochemicals like xanthines, and (poly)phenols in neurodegenerative diseases has been highly established and explored. However, the mechanism of these molecules to cross the membranes reaching the blood and the brain has largely been understudied.
In this work, we used in silico methods to pred...
Diogo Carregosa, I. Moreira, Diogo Rasteiro et al.· Frontiers in Drug Discovery· 0 citations
This study systematically investigates multiple elitism mechanisms for NT within tree-based MO Genetic Programming (MOGP), including NSGA-II population replacement, crowding distance, first-objective, and a novel ideal-point strategy, comparing them against non-elitist NT and standard NSGA-II.
Filipa Vieira Goncalves Pereira, Karina Brotto Rebuli, M. Giacobini et al.· GECCO Companion· 0 citations
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