Author

L. Yao

3 papers indexed here

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Open access Aug 2026

P53 Competitively Binds P300 to Suppress HIF‐1α/TFRC‐Mediated Ferroptosis and Promote Doxorubicin Resistance in Breast Cancer

Doxorubicin (DOX) resistance limits the efficacy of chemotherapy in breast cancer, and suppression of ferroptosis may contribute to this process. This study investigated the role of the Tumor Protein P53 (P53)/E1A‐associated protein P300 (P300)/Hypoxia‐inducible factor‐1α (HIF‐1α)/Transferrin Receptor (TFRC) axis in re...

Xiao-Jie Yu, L. Yao, Shu-Chun Zhang et al. · The FASEB Journal · 0 citations

Open access Sep 2026

Development and internal validation of prognostic nomograms for overall and breast cancer-specific survival in de novo stage IV HER2-positive breast cancer.

The widespread adoption of contemporary human epidermal growth factor receptor 2 (HER2)-targeted therapies has altered survival in HER2-positive metastatic breast cancer, potentially limiting the applicability of older prognostic models. We aimed to develop and internally validate nomograms for overall survival (OS) an...

Xiao-Jie Yu, De-Yuan Fu, L. Yao · Biomolecules & biomedicine · 0 citations

Open access Jul 2026

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

A previously unrecognized transcription‐ubiquitination cascade that modulates Hippo signaling and contributes to breast cancer progression is revealed, highlighting this axis as a candidate therapeutic vulnerability that warrants further validation for limiting metastasis.

An Xu, Xiang-nan Xu, Xiao Huang et al. · Advancement of science · 0 citations