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Author

Laia Llovera

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Open access Jul 2026

Single-molecule m6A profiling reveals position-dependent mRNA regulation and non-canonical roles for Ythdf2 in early embryogenesis

N nanopore direct RNA sequencing on zebrafish embryos across MZT is employed to resolve the interplay between m6A deposition, mRNA clearance, and poly(A) tail length dynamics at single-molecule resolution, and defines the single-molecule logic by which m6A modifications shape transcript fate during vertebrate MZT.

Sarah A. Alshawi, Anna Delgado-Tejedor, Srihari Madhavan et al. · 0 citations

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