Glutamine is the most abundant free amino acid in the body. It plays a central role in cellular metabolism, connecting synthetic and catabolic pathways, and maintaining life activities under physiological and pathological conditions. This review systematically explores the dual role of glutamine metabolism in health an...
Jun-Sheng Zhao, Ya-Jie Lin, Rong Gao et al.· Signal Transduction and Targ...· 0 citations
The PI3K/AKT signaling pathway serves as a pivotal regulatory hub that governs essential cellular processes, including growth, proliferation, metabolism, survival, and migration. In the context of tumorigenesis and cancer development, aberrant activation of this pathway drives malignant transformation, enhances invasiv...
Qingmiao Shi, Jie Liu, Qing-Fei Chu et al.· Signal Transduction and Targ...· 0 citations
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