Lan-nan Yang

The cGAS–STING pathway in pulmonary infectious and sterile inflammation: differences, connections, and therapeutic implications

The cyclic GMP–AMP synthase–stimulator of interferon genes (cGAS–STING) signaling pathway plays a pivotal role in mediating both infectious and sterile pulmonary inflammation, exhibiting distinct dynamic characteristics under different contexts. The activation kinetics of the cGAS–STING pathway are highly dependent on...