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Lan-Yan Hu

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Open access Aug 2026

Glaucocalyxin A sensitizes ovarian cancer cells to PARP inhibitors by inducing DNA damage

Background Poly (ADP-ribose) polymerase inhibitors (PARPi) have demonstrated therapeutic advantages in ovarian cancer (OC) patients with homologous recombination (HR) deficiency. However, their effectiveness is limited in HR-proficient or acquired resistance tumors. Glaucocalyxin A (GLA) is an ent-kauranoid diterpene w...

Ling-Ling Zhuang, Lan-Yan Hu, Qi Chen · 0 citations

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