Open access
Jul 2026
Validation of an UHPLC–MS/MS Assay for the Quantification of Isoniazid and Four Major Metabolites in Human Plasma
An assay consisting of two UHPLC–MS/MS methods was developed and validated to determine concentrations of INH and four of its metabolites in human plasma to help facilitate a better understanding of INH metabolite disposition and relationships with toxicity.
David Nerguizian, Brandon Klein, Farah Abdelmawla et al.
· Biomedical chromotography · 0 citations