Case report
Open access
Sep 2026
Early Coronary Atherosclerosis in Homozygous Familial Hypercholesterolemia: The Importance of Aggressive Lipid Lowering.
BACKGROUND Homozygous familial hypercholesterolemia (HoFH) causes severe lifelong low-density lipoprotein-cholesterol (LDL-C) elevation and accelerated atherosclerosis from childhood. CASE SUMMARY A 10-year-old boy presented with extensive tuberous xanthomas and was diagnosed with HoFH due to bi-allelic pathogenic va...
D. Zachariah, A. Thomas, Lindinkululeko Nkheli et al.
· JACC Case Reports · 0 citations