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Author

Lars Mühlberg

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Open access Aug 2026

Virion-wide interactome mapping of HSV-1 reveals maturation-dependent remodeling and convergent organization of herpesvirus tegument networks

A virion-wide spatial and quantitative protein proximity map of herpes simplex virus 1 (HSV-1) is defined by combining cross-linking mass spectrometry with quantitative proteomics, showing how conserved organizational principles shape virus-specific virion interaction networks during herpesvirus maturation.

Lars Mühlberg, Yannick Jensen, Julia Ruta et al. · 0 citations
Open access Jul 2026

Mapping in-cell protein contact sites reveals hijacking of paraspeckles during influenza A virus infection

In-cell cross-linking mass spectrometry maps protein contacts in influenza-infected human cells, revealing how the virus hijacks host membrane-trafficking factors and dismantles nuclear paraspeckles to enhance replication.

I. Kotova, Lars Mühlberg, Konstantin Gilep et al. · 1 citation

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