Author

Laura E. Downie

2 papers indexed here

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Review Open access Sep 2026

Understanding higher-order aberrations in keratoconus.

Keratoconus is characterized by progressive thinning and increasing irregularity of the cornea, leading to substantial degradation in optical quality through the induction of both lower- and higher-order aberrations (HOAs). In addition to inducing myopic and astigmatic refractive error, asymmetric corneal steepening ge...

Gavin Swartz, Khyber Alam, Alex Gentle et al. · Optometry and Vision Science · 0 citations

Open access Jul 2026

Human cornea harbors tissue-resident memory T cells shaped by systemic immune activation, age and biological sex

The cornea is classically regarded as an immune-privileged tissue. However, recent studies have identified T cells in the healthy human cornea that are absent in specific pathogen-free (SPF) mice. The identity of these T cells, the systemic cues that drive their establishment, and the molecular mechanisms governing the...

Mengliang Wu, Sarah C. Monard, Marina H. Yakou et al. · bioRxiv · 0 citations