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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Laura J. Blair

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Open access Aug 2026

LncRNA Gas5, a Target of the Nonsense-Mediated Decay Pathway in the Brain, Regulates Neuroinflammation and Neurodegenerative Disease Pathways in a Tauopathy Mouse Model

The study demonstrates the potential of selectively stabilizing NMD-target lncRNA Gas5 levels to alleviate early neurodegenerative pathology in tauopathy and disassociated Upf1 and Gas5, thereby hindering NMD.

Meredith Krause-Hauch, Bang-Mei Wang, Rekha S. Patel et al. · 0 citations

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