Open access
Oct 2026
An adenovirus-based mucosal vaccine induces cross-neutralizing antibodies and protects against lethal H5N1 infection in ferrets
Second-generation VXA-H5–02 is a promising vaccine candidate capable of inducing systemic and mucosal immunity, offering broad protection against HPAI, and significantly reduced illness, viral burden, and shedding.
Becca A. Flitter, Ka-Yan Tam, Laura J. Showalter et al.
· Frontiers in Immunology · 0 citations