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Author

Lauren Rice

2 papers indexed here

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Open access Sep 2026

A Research-Integrated Curriculum on CAR-T Cell Therapy

Chimeric antigen receptor (CAR) T cells are patient-derived T cells engineered to recognize specific antigens on malignant cells, representing a major breakthrough in personalized cancer immunotherapy. While CAR-T cell therapy is an established treatment for relapsed or refractory hematologic malignancies, understandin...

Youan H. Khan, Lauren Rice, Melissa C. Srougi · 0 citations
Open access Jul 2026

Direct single-molecule visualization of Hsp90-mediated relief of an Hsp70-folding block

HtpG reduces rebinding of DnaK to folding intermediates while still allowing engagement with misfolded clients, enabling productive refolding in the presence of typically inhibitory concentrations of DnaK and suggests that the number and position of DnaK binding sites on clients provide a mechanism by which proteins ca...

Nicholas R. Marzano, Bailey Skewes, Shannon McMahon et al. · 0 citations

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