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Author

Laurent Parry

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Open access Aug 2026

The GCN2-ATF4 signaling axis orchestrates the hepatic transcriptional stress response to short-term sulfur amino acid deprivation.

GCN2 is established as a major sensor mediating the early hepatic response to SAA deprivation, and a transcriptional program essential for maintaining amino acid homeostasis is defined, highlighting a coordinated adaptive response to acute SAA deprivation.

Valérie Carraro, M. Cherpaz, L. Longechamp et al. · 0 citations